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For researchers whose question genuinely benefits from multi-mechanism investigation, the added complexity of the combination dosing is justified

Y., Kiat, H., Bensoussan, A., Kwan, Y

[DOI] [PubMed] [Google Scholar] 269.Nonn L

Hierarchical clustering of commonly engaged proteins by the fold increase in target engagement in senescent versus non-senescent conditions (referred to as senescence selectivity) identified broadly highly-reactive proteins, clusters of proteins with specificity to certain chemotypes and others (such as GPX4) that were enriched in probes related to three different SCLAs (Fig