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Together, they explore why the current medical system is built to manage illness rather than create health, and what it truly means to take a proactive, data-driven approach to longevity
For patients who cannot tolerate statins or require additional lipid lowering despite maximum tolerated statin therapy, NICE guidance supports several alternative or adjunctive treatments: Ezetimibe : Reduces cholesterol absorption from the intestine and can be used alone or in combination with statins PCSK9 inhibitors (evolocumab, alirocumab): Injectable medications reserved for specific high-risk patients with familial hypercholesterolaemia or established cardiovascular disease who have not achieved targets with other therapies Bempedoic acid : A newer oral option for patients with statin intolerance Inclisiran : An injectable treatment given twice yearly for primary hypercholesterolaemia or mixed dyslipidaemia in line with NICE criteria Icosapent ethyl : For people with established cardiovascular disease and raised triglycerides despite statin therapy Fibrates : Primarily used for severe hypertriglyceridaemia Lifestyle modifications remain fundamental to cholesterol management and should be implemented alongside any pharmacological treatment
The clinical evidence behind semaglutide is exceptional by any standard in medicine
Why we do not build brain-health care around microdosing claims The most concerning part of the microdosing narrative is not that some patients do well on lower doses
Biocompatible polymer minimizes tissue irritation, allowing repeated administration in subcutaneous depots
FAQ Does psyllium husk help with Ozempic nausea
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