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TGF-B has been shown to induce cell death in the rat prostate25 and its receptor has also been found to be down regulated by androgens in this tissue.26 In the immature rat penis, TGF-B1 mRNA is under negative regulation by androgens (Lin, Rajfer, Gonzalez-Cadavid, unpublished)

Current evidence suggests that the effects of GLP-1-related signaling on T-cell biology are context dependent (102,103)

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Editor information Editors and Affiliations Rights and permissions Copyright information 2020 Springer Nature Switzerland AG About this chapter Cite this chapter Maselli, D.B., Camilleri, M

Bottom Line GLP-1 medications do not directly destroy muscle