Mechanism of time-dependent inhibition of 5 alpha-reductase by delta 1-4-azasteroids: Toward perfection of rates of time-dependent inhibition by using ligand-binding energies.Biochemistry1995;34:13453-3459 85
Hair follicle stimulation : Pyo et al
People on GLP-1s were 37% more likely to develop alopecia than SGLT-2 users and 68% more likely than DPP-4 users
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The primary mechanisms include: Enhanced insulin secretion in response to elevated blood glucose levels, helping to lower blood sugar in people with type 2 diabetes Suppression of glucagon release from the pancreas, reducing glucose production by the liver Delayed gastric emptying , which slows the movement of food from the stomach into the small intestine Increased satiety through actions on appetite centres in the brain, leading to reduced food intake The slowing of gastric emptying is particularly significant when considering electrolyte balance
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