Keskin O
Eyvazi S, Vostakolaei MA, Dilmaghani A, Borumandi O, Hejazi MS, Kahroba H, et al
Notably, heightened cholesterol concentrations have been documented within the dermal tissues of those diagnosed with psoriasis (63)
Once activated, TGF- binds to its receptor complex, initiating phosphorylation of Smad2 and Smad3, which then form a complex with Smad4 and translocate to the nucleus and regulate gene transcription (70)
How to use: Apply a thin layer to clean, dry skin at night, massage gently until absorbed, use sunscreen daily, and avoid mixing with stronger active ingredients to prevent irritation
Genotype was determined by probing for 24 single nucleotide polymorphisms (SNPs)