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The p70S6K protein is encoded by the RPS6KB1 gene

Administration of semaglutide at the dose regimen of ~ 90 g/kg/day failed to evidence significant weight loss but more importantly, led to alteration of cortical bone microarchitecture, represented by lower cortical thickness, and ultimately to a significant decrease in bone strength [69]

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This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1720833115/-/DCSupplemental

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