This often coincides with the body initial adaptive response to rapid weight loss
NLRP3-dependent pyroptosis is a significant inducer of abnormal cell death in heat stress-induced liver injury: heat stress triggers caspase-1 activation of the NLRP3 inflammasome, inducing IL-1 release and hepatocyte pyroptosis, leading to severe liver injury [29]
The 2026 American Diabetes Association (ADA) Standards of Care have introduced a unified, clinically actionable framework for its definition, risk stratification, and management, emphasizing a shift from a purely glucose-centric approach to a broader focus on patient safety and cardiovascular, kidney, and metabolic (CKM) health
The crystal structure of human membrane-bound dipeptidase has been reported [49]
Zhang Y, Li L, Xu Y, et al
1 Alexander and colleagues highlighted the implications of these data for both patients and clinicians