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Similarly, lentiviral overexpression of GPx-1 confers a beneficial effect to neuroblastoma cells in culture and to nigral dopaminergic neurons exposed to 6-hydroxydopamine in vivo (308)

However, after a long period of L-DOPA therapy, results can cause a variety of side effects, including hyperkinesia (unpredictable and uncontrollable movements) and on-off phenomena

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Baca also appeared as an actor in the film and as one of its producers

This capability enables the development of drug combinations with synergistic effects, a strategy known as multi-drug targeted pharmacology. Studies have demonstrated that multi-target drugs can more effectively address complex diseases [12]

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