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Journal of Functional Foods 114, 106064

Therefore, we found that acetaminophen was metabolized to AM404, which induces analgesia by directly inhibiting the excitatory synaptic transmission via TRPV1 receptors expressed on terminals of C-fibers in the spinal dorsal horn

Some of the side effects experienced when taking too much include: Nausea Vomiting Poor appetite Constipation Weakness Weight loss Confusion Disorientation Heart rhythm problems Kidney damage Storage Store at controlled room temperature

Even if pigmentation occurs, the long-term risks outweigh any short-term cosmetic benefit

Decombaz, J., Deriaz, O., Acheson, K., Gmuender, B., and Jequier, E