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Since early 2025, the drugmakers have made these medicines available at a discount to patients not using their health insurance, and the prices have come down a bit over time

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Optimization of a novel series of fused -homophenylalanine DPP-4 inhibitors was reported in detail by Jiang et al., leading to the development of -homophenylalanine analogs containing pyrrolidin-2-yl methyl amides (123)