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Front Pharmacol 11:584533 Hu X, Li S, Doycheva DM, Huang L, Lenahan C, Liu R, Huang J, Xie S (2020) Rh-CSF1 attenuates neuroinflammation via the CSF1R/PLCG2/PKCepsilon pathway in a rat model of neonatal HIE

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Important safety considerations include: If you use oral contraceptives, use additional barrier contraception for 4 weeks after starting treatment and after each dose increase Not recommended during pregnancy or breastfeeding Increased risk of hypoglycaemia if used with insulin or sulfonylureas Monitor for signs of pancreatitis or gallbladder disease (severe abdominal pain, persistent vomiting) Regular diabetic retinopathy screening is recommended Arrange baseline and follow-up blood tests with your GP or a private laboratory to monitor HbA1c, renal function, and lipid profile according to NICE guidance

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