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Nature Reviews Disease Primers

Severe adverse events are rare but are closely monitored in clinical trials

L., Barada, F., & Levitsky, A

In the forced swimming test, PE-22-28 reduced immobility time comparably to the SSRI fluoxetine

According to a 2023 review, a compound in wild yams called gracillin possesses anti-inflammatory properties and significantly improved the skin barrier and hydration of mice with atopic dermatitis.10 Additionally, a 2017 study noted that several species of wild yams have demonstrated antimicrobial activity, leading to their use in different forms of traditional medicine as a way to treat skin infections.11 To learn more about the potentially beneficial ingredients in our picks, see each products dedicated section later on

Improved Overall Health and Well-Being Beyond weight loss, B12 injections offer additional health benefits, such as better mental clarity, improved mood, and reduced fatigue