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The agency in October ended the tirzepatide injection shortage prematurely based on representations from drugmakers and incomplete data on demand for the compounded versions of the drug, Scott Brunner, CEO of Alliance for Pharmacy Compounding, another compounding industry group, said in a statement to ABC News

This hormone responds to food intake and plays a critical role in regulating blood sugar levels by stimulating insulin secretion and reducing the production of glucagon, another hormone that raises blood sugar

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Nature 361 , 362365, doi:10.1038/361362a0 (1993)

While they are not reviewed or approved by the FDA for safety or effectiveness, they are made in accordance with strict regulatory guidelines