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Moreover, drugs that may induce hemolytic crisis, such as phenobarbital, sulfonamides, and aspirin, should be avoided for patients with GSSD

Any disruption in this balance is referred to as oxidative stress, which may result from various disorders or dysfunctions in normal physiological systems

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To this end, we performed a preclinical study in 18-mo-old male and female mice treated with vehicle or an IGF-1R mAb (L2-Cmu, Amgen Inc), and determined effects on aging outcomes

Additionally, even after 24 h, the fluorescence signals in the paws of the SP@M group remained strongly maintained