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Cellular and molecular mechanisms of fibrosis

PMCID: PMC6766405

NNMT inhibition increases cellular concentrations of both substrates that the enzyme would otherwise consume: SAM (the universal methyl donor) and nicotinamide (the NAD + salvage precursor)

In a podcast episode released in April 2024, Huberman struck a cautionary note, with the Stanford professor using the words cancer, tumor, and risk, more than three dozen times

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