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Potential interactions include: Metformin (used for type 2 diabetes) Proton pump inhibitors (PPIs) and H2-receptor antagonists (used for acid reflux) Colchicine (used for gout) Nitrous oxide (anaesthetic gas that can inactivate B12) Chloramphenicol (may reduce the haematological response to B12 therapy) If you take any of these medications long-term, discuss B12 monitoring with your healthcare provider

Get it really wrong, and you overshoot your target dose by two or three times, inviting a wave of nausea that could have been avoided entirely

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Dysbiosis is a hallmark of DFUs

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GHK-Cu counters this through p38 MAPK pathway inhibition, which reduces inflammatory cytokine production