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Riool, M., de Breij, A., Kwakman, P., Schonkeren-Ravensbergen, E., de Boer, L., Cordfunke, R.A., et al., Biochem

The synaptic changes Dihexa induces take days to fully develop and persist weeks after the initiating stimulus

It also suppresses the oxidation of low-density lipoprotein, quenches hydroxyl and other reactive oxygen species, and chelates iron in a manner that blocks iron-driven lipid peroxidation

4.1 Disruption of monoaminergic neurotransmission Synthetic cathinones primarily enhance the release and inhibit the reuptake of monoamines, such as dopamine, norepinephrine, and serotonin

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Oxidative stress can damage cells, cause strand breaks in DNA, and interrupt cell signaling