Step therapy (requiring you to try other treatments first) and prior authorizations are also common
Furthermore, the model studied has to be carefully considered since there are differences in the expression of key genes (such as pepT-1) and some effects might depend on the vectoriality of the system (the capacity to differentiate basolateral and apical processes)
Diabetes Care 35:252258 Knudsen LB, Nielsen PF, Huusfeldt PO et al (2000) Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration
Pharmaceuticals 14(6):569
However, a potential increase in the risk of AEs was also noted, including a higher incidence of overall AEs, discontinuation due to AEs, hypoglycemia, and gastrointestinal complications
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