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Electrolyte loss: Vomiting or diarrhea can lead to electrolyte loss

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Here is a simplified version of the titration approach used in the landmark Phase 2 obesity trial published in the New England Journal of Medicine

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In the Hargreaves test, mice with CFA-induced inflammation displayed delayed recovery from heat hyperalgesia following intraplantar vehicle administration

Even though patients with pre-existing conditions are at a higher risk for these vision problems, many patients experiencing these side effects didnt have any major eye problems before starting the medication