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These data show that the BBB is damaged in ex vivo , in vitro , and in vivo models of diabetes in association with brain microvascular endothelial cells/pericyte impairment and inflammation [79]

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Obviously, it may be unclear which one of the parts of peptide + carrier complex would be responsible for the activity (for review, see Urist, 1996)

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doi: 10.1016/J.CELREP.2022.110425 236 ChandraVIbrahimHHalliezCPrasadRBVecchioFDwivediOPet al