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Cardiovasc Diabetol 2019;18:73

Taber DJ, Meadows HB, Pilch NA, Chavin KD, Baliga PK, Egede LE

For example, removal of toxic load can ease compromised neurochemistry

Nephroprotective effects of b-carotene on ACE gene expression, oxidative stress and antioxidant status in thioacetamide induced renal toxicity in rats

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Common experiences after the first injection include: Mild soreness or redness at the injection site (usually resolves within 12 days) Slight improvement in energy levels or mood No immediate noticeable change (particularly common if deficiency is severe) Rarely, mild side effects such as headache or dizziness Some patients report their urine becoming brighter or more intensely coloured following injection, which occurs because excess B12 is excreted renally