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En los ensayos clnicos SURMOUNT y SURPASS, los efectos adversos ms frecuentes de la Tirzepatida fueron gastrointestinales: nuseas (18-22%), diarrea (14-17%), vmito (9-12%) y estreimiento (8-12%), concentrados principalmente en las primeras semanas

[4] [5] These medications also act on the brain's appetite centres, promoting feelings of fullness and reducing hunger signals

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The average duration of diabetes was 6.2 years, and patients were on at least 1,500 mg of metformin with a mean HbA1c of 8%

Additionally, the possibility of treatment selection bias based on unmeasured clinical factors remains