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Therefore, while HRAS mutations are typical of Spitz nevi, demonstrating their presence is no guarantee of a benign lesion, since they can also be found in Spitz melanoma.48,49 However, given that HRAS mutations are found in less than 1% of melanomas,37 their presence in a Spitz tumor is reassuring

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Recombinant production is generally limited to the 20 canonical amino acids unless advanced genetic/enzymatic engineering is used

Wendel WB

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Nevertheless, when reproducible functional connections could be recorded between GLUTag or primary L-cells and ND neurons, blockade of ATP receptors by PPADS was sufficient to reduce the amplitude and area of the neuronal Ca 2+ responses, despite equivalent CNO-induced responses in the monitored L-cells (Fig