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Overview on the recent study of antimicrobial peptides: origins, functions, relative mechanisms and application

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Its potential applications include both therapeutic and cosmetic purposes: Skin Brightening and Tone Enhancement: Glutathione is thought to reduce melanin production by inhibiting the enzyme tyrosinase

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What they found: No serious adverse events triggered by AOD-9604 The most frequent side effects: headache (~5 %), occasional fatigue, at the same frequency as placebo No changes in IGF-1 levels, glycemia, blood pressure, heart rate No signals of cardiovascular, hepatic or renal toxicity Safety profile comparable to placebo Why it matters: From a safety perspective, AOD-9604 is one of the safest peptides in the clinical registry

Samples were then reconstituted in 150L of 40% phosphate-buffered saline (PBS)/60% acetonitrile (ACN) and centrifuged again at 14,000 RPM at 4 C for 10 min