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As a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, tirzepatide works by enhancing insulin secretion, suppressing glucagon release, and slowing gastric emptying
Sources US Food & Drug Administration
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Mounjaro (tirzepatide) European Medicines Agency
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Standard doses of 5001000 mg every 6 hours (maximum 3000 mg daily) are well-tolerated alongside GLP-1 therapy and do not interact with tirzepatide's mechanism
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