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As an active ingredient in supplements it is not recommended, because in addition to its low efficacy a low cyanide pollution also occurs

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Treatment for B12 deficiency without neurological involvement: For patients with haematological manifestations only (macrocytic anaemia) or asymptomatic deficiency, the regimen is hydroxocobalamin 1mg intramuscularly three times weekly for two weeks (total of six injections), followed by maintenance of 1mg every three months for life

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Impaired BBB stability DCE-MRI has exposed increased regional BBB permeability in the cortex and hippocampus in AD, basal ganglia in PD, and white matter in MS

Histology and histopathology , 17 (3), 707714