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A flow chart illustrating selection of the study cohort is shown in Fig

What Happens: Improved insulin sensitivity Better fat metabolism Reduced inflammation Positive effects on lipid profiles Lower blood pressure Cardiovascular benefits What You Experience: More energy Better exercise tolerance Improved lab markers (cholesterol, triglycerides) Reduced risk of metabolic diseases These effects contribute to overall health improvement beyond just weight loss

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Occurrence of gastrointestinal adverse events upon GLP-1 receptor agonist initiation with concomitant metformin use: a post hoc analysis of LEADER, STEP 2, SUSTAIN-6, and PIONEER 6

Additionally, alcohol is a gastric irritant that can amplify the nausea many patients already experience during the first weeks of GLP-1 therapy

As BBC Future pointed out, GLP-1 medications help quiet hunger signals