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Acknowledgements This study was funded by a grant from Marmara University Scientific Research Project Department (Project ID: TYL-2021-10435)

Depletion of L-arginine is associated with exaggerated arginase II activity

This isn't strictly necessary for safety, but it can help some people avoid any minor digestive sensitivity when starting a new routine

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Nondrug therapies with low- to moderate-quality evidence include exercise and neuromodulation with spinal cord stimulation or transcutaneous electrical nerve stimulation

Research shows POEM procedures are effective treatments for conditions that affect the muscles in your esophagus