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The proposed mechanism for the benefits of GLP-1 RAs in HS appears to involve both weight reduction and direct effects on the immune system [33]
At the moment, the primary method of treatment is surgical intervention and hormone therapy, but it is easy to relapse after surgical treatment, which not only costs more but also causes repeated trauma to the patient, especially when patients with OEM and fertility needs are repeatedly stripped by laparoscopic surgery, which will further damage the patients reproductive ability (3, 4)
Compounded medications are not FDA-approved in the traditional sense, but they are manufactured under strict pharmacy compounding regulations by licensed 503A facilities that maintain pharmaceutical-grade quality
In an ad-libitum meal experiment with varying fat content, patients with MC-4R mutations consumed 95% more of the high-fat meal compared to lean controls, and 65% more compared to obese controls