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When semaglutide binds to GLP-1 receptors in your brain, pancreas, and gut, it triggers three key weight-loss mechanisms: increased satiety (feeling full faster), delayed gastric emptying (food stays in your stomach longer), and improved insulin sensitivity (better blood sugar control)

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Fatigue: Some individuals may feel more tired than usual, especially during the early stages of taking the medication

doi: 10.1242/dmm.026609 96 Sobrino CrespoCPerianes CacheroAPuebla JimnezLBarriosVArilla FerreiroE