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LM which are wide, taper distally (are wider at the base- a sign of growing melanoma), or involve the nail folds or hyponychia should raise our concern for melanoma 9

Conversely, only one of six malignant insulinomas was positive with GLP1R immunostaining

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doi: 10.1097/00006454-200103000-00016 80 HegstadK.MylvaganamH.JaniceJ.JosefsenE.SivertsenA.SkaareD

Regular HbA1c monitoring (typically every 36 months) provides the most reliable assessment of long-term glucose control and medication effectiveness