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Another limitation of GLP-1 RAs is that discontinuation commonly leads to substantial body weight regain, and many patients who regain weight subsequently restart GLP-1 RA therapy, resulting in a recurrent cycle of body weight loss and gain [10]

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The CAT-like activity assay of ZFP NPs ZFO and ZFP NPs (200 g mL 1 , final concentration) were added into H 2 O 2 solution with a final concentration of 10 mM, and the dissolved oxygen in the solution was recorded by an oxygen dissolving instrument every 30 s for 5 min

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