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This DA signaling mechanism in the BLA not only facilitates the normal sleep cycle but also contributes to the occurrence of cataplectic attacks in narcoleptics, illustrating its significance in both physiological and pathological aspects of sleep regulation (Hasegawa et al., 2022)

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To counteract fluctuating efficacy in advanced stages of Parkinsons disease, some patients have an internal dopamine-producing pump that delivers dopamine continuously via an implanted probe into the small intestine or under the skin

Understanding the consequences of NNMT inhibition has implications for research into metabolic regulation and potential therapeutic applications

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