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Without enough glutathione, mercury can damage the brain and also take the place of selenium in certain biological pathways.[ref] Related article : Mercury, detoxification, and your genes Alcohol: Acute or chronic alcohol exposure leads to a depletion of glutathione in the liver and liver damage

doi: 10.1016/j.phrs.2022.106550 24 SalcedoITweedieDLiYGreigNH

Jensen MH, Kjolby M, Hejlesen O, et al