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[Abstract] IF analysis revealed a notable increase in collagen I fluorescence intensity in the HFSFs treated with ARP-100 (ARP, 100 M, 24 h), whereas a reduction in collagen I fluorescence intensity was found in HFSFs treated with glutathione oxidized (GLU, 2.48 mg/mL, 24 h)

N-acetylcysteine (NAC) has been shown to treat glutathione deficiency 20 in some studies

doi: 10.1016/j.dld.2014.01.159 83 TofaloRCocchiSSuzziG

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Patients with chronic pancreatitis have lower levels of glutathione, cysteine, and glycine.[ref] Increasing cysteine levels with NAC is protective against pancreatic damage.[ref] Schizophrenia: Several research studies show that people with schizophrenia have lower glutathione levels in certain regions of the brain.[ref] In aging: The studies on glutathione in aging show that there is usually a general decrease in serum glutathione levels as we age