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For this reason, otherwise healthy individuals may want to avoid taking high doses of NAC until more information is available

The most common complaints among these individuals were fatigue, difficulties with concentration (often described as "brain fog"), depression, anxiety, and trouble sleeping

Instead, pause at your current dose until symptoms improve, which typically takes 12 weeks

Higher doses of tirzepatide are associated with increased rates of nausea and vomiting, which is why Zepbound therapy follows a gradual dose-escalation schedule

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Br J Haematol 2004