The body does not exclusively target fat stores during periods of severe energy restriction
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Primary carnitine deficiency PCD is a rare genetic disease caused by mutations in the SLC22A5 gene, which leads to dysfunction of the carnitine transporter OCTN2, thereby hindering the entry of carnitine from the blood into cells and the reabsorption of carnitine by the kidneys
In the present study, leukopenia occurred until 9 h after the immune challenge, which is caused, in part, by an uneven distribution of leukocytes towards the marginated pool due to aggregation, margination, and adhesion of monocytes and granulocytes to the endothelium (27)
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Both PLT ( Supplementary Table 1 ) and PCT ( Supplementary Table 1 ) decreased after LPS administration, reaching their nadir at 6 h and 12 h, respectively and returned thereafter to pre-challenge levels