tirzepatide vs dulaglutide vs. Dulaglutide: Cardiovascular Outcomes in Type 2 Diabetes Tirzepatide demonstrates cardiovascular protection in

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Ohlsson, L., Kohan, A

Unlike older medications that target a single hormonal pathway, tirzepatide activates both GLP-1 and GIP receptors, enhancing the body's natural ability to feel full and process glucose more efficiently

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Supporting this, the SUSTAIN-6 cardiovascular outcomes trial found that once-weekly semaglutide drugs carry a higher risk of diabetic retinopathy progression