The anatomy itself creates challenges
Immune infiltrates in ectopic lesions include increased macrophages, mast cells, and memory CD4+ T cells, alongside decreased NK cells and plasma cells, mirroring autoimmune pathologies ( 2.2.4 Chronic inflammatory milieu Pro-inflammatory cytokines (TNF-, IL-6, IL-1, IL-8, IL-17) and chemokines (RANTES) accumulate in peritoneal and follicular fluid, creating a hostile microenvironment
One of the reasons is that the outcome of paracetamol-induced liver disease is most probably an interplay of several signaling events
Davani-Davari, D., Negahdaripour, M., Karimzadeh, I., Seifan, M., Mohkam, M., Masoumi, S
This may be more difficult for vegetarians or vegans
That leaves 9mg potentially beyond its safe use date