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However, due to the absence of centrioles, the resultant spindle morphology is reduced in size, and the characteristic astral microtubules at the poles are absent, contributing to the increased instability of spindle assembly in human oocytes

Diagnostic procedures

However, the strength of the findings presented in both studies is limited by inadequate data and unknown risk of bias (Timmer et al., 2016)

Signaling Pathways of the Insulin-like Growth Factor Binding Proteins

Peripherally, pancytopenia is most often observed, but only 12 of the major cell types (erythrocytes, leukocytes, platelets) may be depressed in some cases

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