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Seale, L

It remains unclear whether diet-induced differences in microbial composition, or other mechanisms such as transcriptional or post-transcriptional regulation of microbial enzymes (or more likely a combination), are responsible for the functional differences observed

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& Hennige, A

NNMT (nicotinamide N-methyltransferase) is a cytosolic enzyme that catalyzes a specific methylation reaction: it transfers a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing two products 1-methylnicotinamide (1-MNA) and S-adenosylhomocysteine (SAH)