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Nutritional deficiencies: Strict vegetarians and vegans often qualify for B12 injections, as B12 is predominantly found in animal products

What the clinical data shows From the Phase 2 trial: Two patterns stand out

If you're plant-based or your gut doesn't absorb nutrients well, you're at higher risk for running low

Semaglutide (Wegovy) is FDA-approved for chronic weight management (with criteria) and has strong clinical trial evidence for meaningful average weight loss when paired with lifestyle support

The clinical significance of this difference for most patients is debated, and for the majority of people either form is adequate

The injection itself takes only a few minutes, with minimal discomfort