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Potential Innovations Drug Development : Developing safer GLP-1 receptor agonists can provide semaglutides benefits without associated appendicitis risks

Weekly semaglutide injections induce and prolong the effects of elevated GLP-1, such as: Reduced Insulin Resistance High Metabolism the ability to burn calories Slower Gastric Emptying Process food transport from the stomach to small intestines (prolongs the feeling of fullness ) Increased Satiety smaller portion sizes satisfy hunger Smaller Appetite decreased desire to eat How does Zepbound work

Until more definitive evidence becomes available, clinical decisions must be made on an individual basis, weighing the potential benefits against theoretical and observed risks

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doi: 10.1016/j.tins.2009.11.003 84 HolscherC