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Difficulties arising from potential immunogenicity, large molecular weight, need for carriers for their delivery and instability in vivo are well recognized [188]

Co- treatment of 4-phenylbutyrate and AEOL10150 a catalytic antioxidant to ALS mice had a collective effect on survival time and there was a reduction in the markers of oxidative damage in the lumbar spinal cord (Petri et al., 2006)

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High blood potassium levels and symptoms related to polycythemia vera, a blood disorder, can occur

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