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The reporting of studies conducted using observational routinely collected health data statement for pharmacoepidemiology (RECORD-PE)

Kavita Sharma, associate professor of medicine at Johns Hopkins University School of Medicine in Baltimore

The net result was a loss of 5.6% of body weight in semaglutide participants and 0.1% in placebo participants

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438,439 GLP-1 can also enhance endothelial function by promoting the production of NO, possibly through activating eNOS, thereby affecting vasodilation, anti-inflammatory actions, and anti-atherosclerosis

Anorgasmia and GLP-1 medications: what the case reports reveal Perhaps the most concerning sexual side effect associated with GLP-1 agonists is anorgasmia, the inability to achieve orgasm despite adequate stimulation and desire