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The -glutamyl cycle was initially postulated by Meister as a mechanism for amino acid transport (76)

In the pathogenesis of psoriasis, they curtail the expression of IL17A and chemokines through the modulation of the IL23/Th17 axis [372]

GSH, an endogenous low-molecular-weight thiol-containing compound, plays an essential role in cellular redox reactions and protects cells from ROS 37

Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells

PMID 6727660

But in MCAS, these cells release histamine and other chemical mediators too frequentlyoften in response to foods, environmental triggers, stress, or even without a clear cause