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Nausea rates are 28% for Retatrutide versus 44% for Semaglutide (Wegovy) at standard doses

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What stands out to me is the nuance in balancing statistical safety with the real-world complexity of patients who often carry both metabolic and psychiatric risk factors

target is at least greater than 7% Overweight/obesity with baseline BMI ideally 25-30% +range Duration of diabetes does not affect parameters, but is usually used in patients when Metformin has proved ineffective/inadequate