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However, 13-week Phase 2 data in 125 patients cannot be meaningfully compared to 68-week Phase 3 data in 1,961 patients

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Recent studies have suggested that IF inhibits the nuclear factor kappa-B signaling pathway, which is an important regulator of downstream parameters including TNF- and IL-6 (25), which is consistent with the results that IF could partly eliminate the inflammation caused by adipose tissue, with lower CRP and TNF- (26)