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Yang X, Gu J, Lv H, et al

N Engl J Med 2013;369:224-32.ArticlePubMed 452

Withdrawal occurs in various scenarios, such as missing doses, abruptly discontinuing (known as quitting cold turkey), or switching to a different antidepressant

While current methods have transformed modern therapeutics, they remain constrained by poor oral bioavailability, stability challenges, cold-chain dependence, and limited patient acceptability associated with injectable administration, according to a review in AAPS PharmSciTech

The amount of drops may vary based on the patient and progression through treatment

Ensure adequate protein intake (especially during rapid weight loss phases) and maintain consistent hydration, as both support metabolic stability and thermoregulationaim for 810 glasses of water daily and include protein-rich meals to preserve lean muscle mass that generates body heat