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As a result, testes stop producing testosterone, leading to low endogenous testosterone levels, low sperm count and eventually infertility

10.1016/S0891-5849(01)00480-4 Free Radic

44 (Suppl

Conjugating TEM8-targeting antibodies with cytotoxic monomethyl auristatin E was successful in specifically directing the drug to the tumor microenvironment of orthotopic tumors and patient derived xenografts, significantly inducing regression or eradication of tumor growth in pre-clinical models [323]

doi: 10.1016/0196-9781(88)90216-1

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